Databases open to sharing with the community.

 

 

 

 

As members of the research community at large, CIPAC understands that the sharing of appropriate research data has the ability to amplify research by providing strong statistical significance and trend identification. As many research agencies now require their funded researchers to share not only their findings, but their data and databases, this important raw information can be made available to others. Below is a listing of the databases which, with full permission of the Prinicipal Investigators, CIPAC will facilitate its sharing with others in the research community. To apply for access to these databases or to find out more information about the study, please follow the links below.

 

TEMPO-1  

TNK-tPA Evaluation for Minor ischemic stroke with Proven Occlusion is a dose-escalation safety study.  Two dose tiers at 0.1mg/kg and 0.25mg/kg will be completed sequentially.  The primary outcome is safety and secondary outcomes are for efficacy.

Principal Investigators: Michael D Hill and Shelagh Coutts

Core Imaging Lab: Calgary 
Number of Patients: 35
Number of Sites: 3 (in Canada)
Imaging Protocol: Baseline CT/CTA, 4-8hr followup CTA, 24hr followup CT or MRI

Request access to database                          Contact PI                        Study webpage
ESCAPE  

Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times is a parallel group, open-label study, with 1:1 randomization and blinded outcome evaluation.  

Principal Investigators: Michael D Hill, Mayank Goyal, and Andrew M Demchuk 

Core Imaging Lab: Calgary 
Number of Patients: 35
Number of Sites: 30 (in Canada, United State and Europe)
Imaging Protocol: Baseline CTA, CTA and/or CTP

Request access to database                          Contact PI                        Study webpage
PRoVe-IT  

Precise and Rapid Assessment of Collaterals Using Multi-phase CTA in the Triage of Patients with Acute Ischemic Stroke of IA Therapy (PRove-IT). Prospective observational cohort study.

Principal Investigators: Bijoy Menon

Core Imaging Lab: Calgary 
Number of Patients: 500
Number of Sites: >9 (in Canada and United States)
Imaging Protocol: Baseline CTA and follow up CTA

Request access to database                          Contact PI                        Study Webpage
DOUBT  

Diagnosis Of Uncertain-origin Benign Transient neurological symptoms. Prospective observational cohort study.

Principal Investigators: Shelagh Coutts

Core Imaging Lab: Calgary 
Number of Patients: 1000
Number of Sites: 12 (in Canada, Czech Republic, Australia)
Imaging Protocol: Baseline MR

Request access to database                          Contact PI                        Study Webpage
TEMPO-2  

Based on the success of TEMPO-1. A randomized-controlled trial of TNK-tPA versus standard of care for minor ischemic stroke with proven occlusion.

Principal Investigators: Shelagh Coutts

Core Imaging Lab: Calgary 
Number of Patients: 1274
Number of Sites: 4 (in Canada)
Imaging Protocol: Baseline CT/CTA/CTP, 4-8hr CTA, 24hr CT or MRI

Request access to database                          Contact PI                        Study Webpage
SPECTRA  

Spectrometry for TIA Rapid Assessment (SPECTRA) project. Verification and Validation study.

Principal Investigators: Shelagh Coutts

Core Imaging Lab: Calgary 
Number of Patients: 1600
Number of Sites: 2 (in Canada)
Imaging Protocol: Baseline MR or CT

Request access to database                          Contact PI                        Study Webpage